Reliable, Automated Formulation Preparation

The Matrix Maker™ system is a formulation preparation engine for high-throughput crystallography and formulations labs. Using Crystal Miner™ software, it solves the crystallization screen formulation bottleneck by allowing researchers to design and produce any desired reagent kit from up to 60 individual chemical stock solutions.

The system is a  unique combination of 30 precision syringe pumps each with 9-position valve heads, innovative plumbing and a high-resolution gantry. It can accurately deliver chemical stock solutions under sterile conditions to any plasticware well or tube position.

The patented design allows the Matrix Maker to handle highly viscous solutions with excellent dispensing accuracy. All of the stock solutions are dispensed by positive pressure displacement, a design which eliminates aspiration problems and costly tip waste.  From start to finish, the robot can produce a formulation matrix of 96 different cocktails in 35 minutes or less. 

Large Protein crystal grown using a Precipitant Synergy screen produced on the Matrix Maker.	The Matrix Maker gantry with 60 outlet lines and needles allows for flexible dispensation of reagents into a variety of defined plasticware devices.